Thursday, August 8, 2019
How can the treatment of cancer with recombinant antibodies be Essay
How can the treatment of cancer with recombinant antibodies be improved - Essay Example The process focuses on the production of recombined genes leading to the rapid re-production of genetically modified bacteria causing the process to continue further by virtue of reproduction of DNA segments and recombination with original DNA. Antibodies, resembled to ââ¬ËYââ¬â¢ shape, refer to the protein molecules with a crucial role for keeping and restoring our health to its optimum state by identifying and attacking foreign bodies entering into our health system. Several types of antibodies have been acknowledged in scientific studies, each type has the capability to recognize unique and distinctive antigens and to get combined with the targeted antigens by using the method of molecular structuring leading to the eventual destruction of several antibodies of foreign objects like viruses or bacteria. There are several reasons associated with the advantages of application of recombinant antibodies such as there no animals are needed so inflexibility regarding the issue of u sing animals for human research could possibly be avoided. Secondly, the manufacturing time for producing recombinant antibodies is significantly less compared to the conventional method. Thirdly and most importantly the quality of the product is far more acceptable than that of the traditional one by virtue of the production of a large number of various antibodies working against a particular antigen in a single selection procedure is possible. The aim of this research is to describe the development of new role and techniques of producing recombinant antibodies in cancer treatment. The library structure of monoclonal antibodies (mAbs) may be biased towards specificities in particular present in the immunized fragments of immunized animals (Clackson et al, 1991) or naturally immunized or contaminated individuals (Burton et al, 1991). These libraries are primarily structured from VH and VL gene pools which are derived on the basis of either PCR-based (Orlandi et al,
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